Jayden did really well with the CBD oil when we first started it last year. As we increased the oil, she continued to do well. Then after about 4 months, she seemed to become immune to the oil. We ran out of the oil after 5 months of use and we decided to give it a break. Jayden has autism and has severe meltdowns. The days that the oil seemed to get in her system, she had less severe meltdowns. She has once again increased her speech. We are super excited about starting the CBD oil therapy again!